Guggi began his career as a musician with the cult band Virgin Prunes, notorious for their performative spectaculars on the European underground, before concentrating full time on painting. From the early tentative explorations in the mid 1980’s, Guggi, - primarily self-taught - has evolved into one of the most accomplished and recognized painters of his generation.

Guggi has exhibited widely since the 1990’s. Most notably he has had solo shows in Yoshii Gallery, New York (2010); John Rocha Building, London (2010); Kerlin Gallery, Dublin (2009, 1993, 1990); Osborne Samuel Gallery, London (2004); Solomon Gallery, Dublin (2005, 2002, 2000); Tony Shafrazi Gallery, New York (2001). Guggi has participated in a number of two person shows with Sybille Ungers including Ric Urmel Gallery, Gent, (1991) and Gallerie Schurr, Stuttgart (1990).

Select group exhibitions include National Gallery of Ireland, Dublin (2008); Irish Museum of Modern Art, Dublin (2004); Castle of Good Hope, Cape Town, South Africa, (2004). Guggi has permanent installation work at Beacon Court and the Clarence Hotel, Dublin and his work is collected by both private and corporate collections in Ireland and abroad, including Château La Coste, France and the Irish Museum of Modern Art, Dublin.